GMWatch flags CRISPR off-target proteins

- GMWatch posted a safety alert this week saying some CRISPR edits can create unintended off‑target protein effects that show up at the protein, not just DNA, level. - The post emphasized protein‑level risks that standard DNA-focused off‑target screens might miss, urging broader safety assays in preclinical work. - Those protein-level concerns add a new layer to regulatory review and trial monitoring for CRISPR programs. (x.com)