Zyphra subleases Salesforce Tower
Zyphra quietly subleased an entire floor in Salesforce Tower after hitting a $1B valuation — a recent sign that pockets of strong capital and office expansion still exist in the Bay Area. That kind of local expansion feeds hiring and infrastructure demand in the region. (bizjournals.com)
Zyphra relocated from Palo Alto to San Francisco in January and now lists 415 Mission St., Floor 44 as its headquarters on the company website. (hoodline.com) The startup subleased the entire 44th floor of Salesforce Tower — a space Hoodline describes as part of the building’s marketed “Sky” levels — and plans to use the floor for research, engineering and expanded operations. (hoodline.com) Zyphra closed a Series A at a $1 billion post‑money valuation on Oct. 1, 2025, a milestone noted in press materials tied to its infrastructure partnership. (newsroom.ibm.com) Under a multi‑year agreement, IBM committed to provision a large, dedicated cluster of AMD Instinct MI300X GPUs on IBM Cloud for Zyphra, with the initial phase deployed in early September 2025 and planned scaling into 2026. (newsroom.ibm.com) Zyphra and its partners announced ZAYA1 on Nov. 24, 2025, describing it as the first large‑scale Mixture‑of‑Experts foundation model trained entirely on AMD MI300X hardware. (prnewswire.com) The full‑floor move aligns with a 2025 trend in which AI tenants accounted for more than 800,000 square feet of leasing across Q1–Q2 and helped drive roughly 1.1 million square feet of net positive absorption in the Bay Area, concentrating demand in trophy towers like Salesforce Tower. (bisnow.com)
