Bruker demos SWILE automating sample prep

- Bruker is showcasing FLEX SWILE, a Chemspeed-built system that automates solid sample preparation for nuclear magnetic resonance and liquid chromatography-mass spectrometry workflows. - The setup dispenses powders directly from source vials into NMR tubes or LC vials at plus-or-minus 10 micrograms, using disposable glass tips. - Bruker is pushing automation deeper into research and GMP labs through its Chemspeed platform. (bruker.com)

Before the demo, the bottleneck is simple: many nuclear magnetic resonance and liquid chromatography-mass spectrometry samples are still weighed, transferred, and dissolved by hand. Bruker is now pitching FLEX SWILE to automate that step. (bruker.com) (chemspeed.com) FLEX SWILE is sold through Bruker’s automation portfolio and built on Chemspeed’s gravimetric dispensing technology, which measures solids by weight rather than by scoop size or operator judgment. Bruker says the system is designed for both research and good manufacturing practice, or GMP, environments. (bruker.com 1) (bruker.com 2) In practice, the machine picks powder from a source vial, dispenses it into a nuclear magnetic resonance tube or liquid chromatography vial, adds solvent, and can stir to dissolve the sample. Chemspeed says the workflow can also read barcodes and connect to autosamplers from Agilent, Shimadzu, Thermo, and Waters. (chemspeed.com) The core claim is precision on very small amounts. Bruker says FLEX SWILE handles sample sizes from micrograms to milligrams, while Chemspeed lists a dispensing range from hundreds of micrograms to about 5 milligrams at plus-or-minus 10 micrograms resolution. (bruker.com) (chemspeed.com) That matters because sample prep errors can distort what the instrument sees before a spectrum or chromatogram is ever collected. Both companies frame the pitch around replacing time-consuming manual handling with repeatable dosing and fewer operator-driven mistakes. (bruker.com 1) (bruker.com 2) Chemspeed says the system uses disposable glass tips and a second analytical on-deck balance to cut cross-contamination risk and verify the amount dispensed. A tilt-and-shake rack loosens powders before pickup, which is useful when solids clump or settle in storage vials. (chemspeed.com) Bruker is not presenting SWILE as a stand-alone gadget so much as one module in a broader automated lab stack. Its automation pages pair Chemspeed robotics with Bruker instruments and software, including links to laboratory information management systems and electronic lab notebooks. (bruker.com 1) (bruker.com 2) Chemspeed’s own Bruker pages make the target customer clear: labs running high-throughput analytical work that want unattended preparation and reproducible inputs into NMR and LC/MS. The sales argument is less about a new detector and more about making sure the sample reaching the detector is prepared the same way every time. (chemspeed.com) (chemspeed.com)

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