St. Olaf study: creatine helps sleep, strength

- St. Olaf College researchers reported that creatine plus resistance training helped peri- and postmenopausal women build lower-body strength, with sleep gains showing up in perimenopause. - The 14-week study followed 15 women taking 5 grams daily; strength improved on dynamometer testing, and sleep quality improved in perimenopausal participants. - It matters because creatine research is widening beyond gym performance, but the evidence is still early and sample sizes remain small.

Creatine is usually filed under gym-supplement, muscle-builder, bro-science-adjacent powder. But the interesting news here is about menopause — and about what happens when a very old supplement gets tested in a group that sports nutrition mostly ignored for years. A small 2025 study from St. Olaf College found that creatine, paired with resistance training, improved lower-body strength in peri- and postmenopausal women, and also seemed to help sleep in the perimenopausal group. ### What did St. Olaf actually test? The study was a 14-week, repeated-measures trial in 15 women with a mean age of 54 — 5 in perimenopause and 10 in postmenopause. Everyone took 5 grams of creatine monohydrate daily and followed a twice-weekly total-body strength program. The researchers tracked body composition, cognitive measures, estrogen, mood and sleep questionnaires, and muscle strength using an isokinetic dynamometer. ### What improved? The clearest signal was lower-body strength. The paper says creatine supplementation led to significant gains across peri- and postmenopausal participants, especially on one knee extensor torque test. Sleep also moved in the right direction for the perimenopausal women, with a statistically significant improvement in sleep quality. Estradiol did not change significantly, and most other tests did not show clear effects. ### Why would creatine affect sleep at all? Creatine helps cells recycle energy fast. Most people think about that in muscle, but the brain uses the same energy-buffer system. That matters in menopause because hormonal shifts can show up as fatigue, poorer recovery, brain fog, and disrupted sleep. The idea is not that creatine is a sedative — it isn’t — but that better cellular energy handling might make the system and it's the broader direction of the research. ### Is there any brain evidence behind that? A separate 2025 randomized controlled trial gives that idea a bit more weight. In the CONCRET-MENOPA study, 36 peri- and menopausal women were split across creatine and placebo groups for 8 weeks. The medium-dose creatine hydrochloride group improved reaction time by 6.6% versus 1.2% with placebo and showed

Get your own daily briefing

Scout delivers personalized news, insights, and conversations tailored to your role and industry.

Download on the App Store

Shared from Scout - Be the smartest in the room.