Stem cells engineered as drug factories

- Researchers edited hematopoietic stem cells so they continuously secrete anti‑HIV antibodies for extended periods in mice, acting like persistent drug factories. - In preclinical studies the engineered cells produced months‑long antibody levels and a new in‑body delivery method reportedly tripled editing effectiveness. - The approach could convert chronic dosing into one‑time cell therapies, though human safety and long‑term control remain to be shown. (x.com)