Abiogenesis odds dwarf 10^-20

- Commentators cited the classic abiogenesis estimate that a specific 150‑amino‑acid protein forming by chance is about 1 in 10^195, an astronomically small probability. (x.com) - That 1/10^195 figure dwarfs the 1‑in‑10^20 rare-event sampling challenge researchers sometimes aim to map, highlighting infeasibility without strong priors or guided mechanisms in origin models. (x.com) - The comparison underscores why algorithmic biases, physical constraints, or mechanistic guidance are essential to study extremely unlikely molecular transitions. (x.com)